who we are

Connecting genetic variation to development, function and disease through quantitative genomics

The Conrad Lab integrates human genetics, reproductive and developmental biology, and primate genomics to understand how genetic variation shapes biological function. We develop and apply quantitative methods to uncover patterns in complex genomic data and translate them into biological and clinical insight.

what we study

Research

Our research spans three interconnected areas that link genetic discovery with the molecular, cellular, and developmental mechanisms underlying reproductive and primate biology.

QUANTITATIVE GENOMICS & METHODS DEVELOPMENT

Connecting genetic variation with biological function

MALE INFERTILITY & REPRODUCTIVE GENETICS

Discovering genetic causes of male infertility and translating those discoveries toward clinical use

GEMINI

TESTIS DEVELOPMENT & PATHOLOGY

Understanding how the testis develops and how disruptions in developmental and cellular processes contribute to infertility and disease

PRIMATE GENETICS, GENOMICS & DEVELOPMENT

Using NHPs to investigate development, genetic variation, and biological processes that cannot readily be studied in humans

dGTEx * MCC

Interconnected biology informs and advances each area

how we do it

Methods & Approaches

We combine leading-edge genomic technologies with quantitative approaches and computational tools developed in our lab to turn complex biological data into interpretable insights.

TOOLS & RESOURCES WE DEVELOP

COMPUTATIONAL METHODS

Developing quantitative approaches to analyze and interpret complex biological data

INTERACTIVE DATA RESOURCES

Building interactive resources that make complex genomic data accessible and useful

TECHNOLOGIES WE USE

SINGLE-CELL GENOMICS

Resolving cell types, states, and developmental programs at single-cell resolution

SPATIAL TRANSCRIPTOMICS

Connecting gene expression with cellular organization and tissue architecture

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