A naturally occurring variant of MBD4 causes maternal germline hypermutation in primates

Alex’s paper is now available online in Genome Research. Congratulations! Abstract As part of an ongoing genome sequencing project at the Oregon National Primate Research Center, we identified a rhesus macaque with a rare homozygous frameshift mutation in the gene methyl-CpG binding domain 4, DNA glycosylase (MBD4). MBD4 is responsible for the repair of C […]