The origins and functional effects of postzygotic mutations throughout the human life span

Former grad student Nicole’s paper on detecting and analyzing PZMs in GTEx data is now available online in Science. Congratulations! Abstract Postzygotic mutations (PZMs) begin to accrue in the human genome immediately after fertilization, but how and when PZMs affect development and lifetime health remain unclear. To study the origins and functional consequences of PZMs, […]